Land application of organic materials for soil management in Nebraska is important. The availability of applied organic N and the fertilizer N substitution values of applied organic materials is not well predicted. The uncertainty of applied organic N availability leads to over-application of fertilizer N resulting in low efficiency of applied N use. Research has been done to validate or adapt canopy sensor guided in-season N application practices for fields with manure or other organic material applied, and to improve the prediction of the fertilizer N substitution values for organic materials.